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Keywords: fibromyalgia; palmitoylethanolamide; melatonin; nutraceuticals; soreness; sleep; quality of life1996). Oral PEA also lessened paw oedema induced by carrageenan, dextran and formalin, suggesting which the compound right down‐modulates mast mobile activation in vivo2007) Which exogenously administered PEA might be an effective substitute
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2005). These benefits were not astonishing if we consider that PEA is a poorly water‐soluble compound, which could limit its oral absorption and bioavailability, Nevertheless they can also advise a brief‐lived motion of PEA, in arrangement with The truth that this compound is degraded by two unique hydrolases, that's, NAAA and FAAH. Later on, G